Case Report

Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion (MERS) Associated With HHV-7 in a Immunocompetent Adult, A Case Report and Literature Review

10.4274/atfm.galenos.2021.48303

  • Burcu Çalışkan Demirkıran
  • Aysun Yalçı
  • Mine Filiz
  • Cumhur Artuk
  • Cemal Bulut
  • İsmail Yaşar Avcı

Received Date: 19.03.2021 Accepted Date: 11.05.2021 J Ankara Univ Fac Med 2021;74(1):103-107

A 26-year-old male without any chronic disease was admitted to the hospital with fever, headache and diplopia. Neurological examination was normal and there were no signs and symptoms of meningeal irritation. On brain magnetic resonance imaging (MRI), a mild transient cytotoxic lesion (MERS-type 1) was observed in the splenial region of the corpus callosum. Mononuclear pleocytosis, increased protein level and HHV-7 DNA positivity were detected in the cerebrospinal fluid (CSF) examination. Clinical improvement was observed while receiving empirical acyclovir treatment for HSV-1 encephalitis with CSF findings. We found this case worth presenting because there was an HHV-7 encephalitis case with mild transient splenial lesion in an immunocompetent individual.

Keywords: Human Herpesvirus 7, Encephalitis, Corpus Callosum

Full Text (Turkish)